Microarray analysis of neonatal brain exposed to cadmium during gestation and lactation
Akiko Honda1, Chiho Watanabe, Minoru Yoshida
1Environmental Health Division, Department of Environmental Engineering, Graduate School of Engineering, Kyoto University, Kyoto, Japan.
The Journal of Toxicological Sciences
|January 30, 2013
Abstract:
DNA microarray containing 30,000 genes was used to monitor the transcriptional response of the neonatal brain after cadmium (Cd) exposure. C57BL/6J pregnant mice were exposed to Cd (10 ppm) during gestation and lactation via drinking water. In a comparison between the Cd-exposed neonatal brain and control, three genes including transferrin receptor (Tfrc) were up-regulated and one gene was down-regulated.
