Microarray analysis of neonatal brain exposed to cadmium during gestation and lactation

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Akiko Honda1, Chiho Watanabe, Minoru Yoshida

  • 1Environmental Health Division, Department of Environmental Engineering, Graduate School of Engineering, Kyoto University, Kyoto, Japan.

The Journal of Toxicological Sciences
|January 30, 2013
PubMed

DNA microarray containing 30,000 genes was used to monitor the transcriptional response of the neonatal brain after cadmium (Cd) exposure. C57BL/6J pregnant mice were exposed to Cd (10 ppm) during gestation and lactation via drinking water. In a comparison between the Cd-exposed neonatal brain and control, three genes including transferrin receptor (Tfrc) were up-regulated and one gene was down-regulated.

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