Goblet cell carcinoid of the vermiform appendix - a case report

Area of Science:

• Gastroenterology
• Oncology
• Pathology

Background:

• Goblet cell carcinoid (GCC) is a rare neuroendocrine tumor originating in the vermiform appendix.
• GCC exhibits uncertain clinical behavior and is almost exclusively found in the appendix.

Observation:

• A 60-year-old female presented with symptoms mimicking acute appendicitis.
• Microscopic examination revealed features of acute appendicitis alongside scattered clear cytoplasm cells and single cells without atypia.

Findings:

• The appendix displayed histological characteristics of both acute appendicitis and goblet cell carcinoid.
• The presence of atypical cells, though scattered, prompted further investigation.

Implications:

• This case underscores the importance of thorough histopathological examination for diagnosing rare appendiceal tumors.
• Right hemicolectomy was performed, indicating the need for potentially aggressive surgical management in suspected GCC cases.
• Accurate diagnosis of GCC is crucial for determining appropriate patient management and prognosis.