Related Experiment Videos
Cerebral venous-sinus thrombosis: a case series analysis
Nahid Ashjazadeh1, Afshin Borhani Haghighi, Maryam Poursadeghfard
1Shiraz Neurosciences Research Center, Department of Neurology, Shiraz University of Medical Sciences, Shiraz, Iran.
Iranian Journal of Medical Sciences
|January 30, 2013
Summary
Oral contraceptive use is a significant risk factor for cerebral venous-sinus thrombosis (CVST) in women. Awareness and education are crucial for preventing this serious condition.
Area of Science:
- Neurology
- Vascular Medicine
- Public Health
Background:
- Cerebral venous-sinus thrombosis (CVST) is an uncommon yet significant cause of stroke, particularly affecting young women.
- Understanding the risk factors and clinical profile of CVST is crucial for timely diagnosis and management.
Purpose of the Study:
- To evaluate the demographic, etiologic, radiological, and prognostic characteristics of patients with cerebral venous-sinus thrombosis.
- To identify key factors associated with CVST, especially in the context of oral contraceptive use.
Main Methods:
- A retrospective descriptive-analytical study was conducted.
- 124 patients diagnosed with cerebral venous-sinus thrombosis between January 2000 and March 2008 were analyzed.
Main Results:
- The majority of patients (70.16%) were women, with a mean age of 34.01 years.
- Oral contraceptive use was reported in 65.51% of women, with some using it for religious observances.
- The superior sagittal sinus was the most commonly affected area. High mortality (14.51%) and morbidity (35.48%) rates were observed. Stupor, coma, and hemorrhage on CT scans were poor prognostic indicators.
Conclusions:
- Oral contraceptive pills are a primary factor linked to cerebral venous-sinus thrombosis.
- Clinical manifestations and prognostic factors align with existing literature.
- Public health initiatives are needed to educate women about CVST risks and prevention strategies.
Related Concept Videos
01:20Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
01:30Venous Thrombosis I: Introduction
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
01:22Cerebral Edema ll: Pathophysiology
Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...
01:29Venous Thrombosis III: Interprofessional Care
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
01:19Veins of Head and Neck
The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
01:14Increased Intracranial Pressure l: Introduction
Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...