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Updated: May 14, 2026
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Clinical manifestations and MRI features of vaginal endodermal sinus tumors in four children
Qing-Yu Liu1, Li Huang, Xiao-Feng Lin
1Department of Radiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Xi Road, Guangzhou, 510120, Guangdong Province, China. liu.qingyu@163.com
Background:
Vaginal endodermal sinus tumor is a rare entity.
Objective:
The purpose of this study was to report the clinical manifestations and MRI features in a case series.
Materials And Methods:
Children with vaginal endodermal sinus tumor admitted to our hospitals between January 2008 and August 2012 were included. MRI was performed in all four children and diffusion-weighted imaging was performed in two children.
Results:
Four children, mean age 14 months, were included. All had a history of vaginal bleeding. Serum alpha-fetoprotein was significantly elevated on admission. Relative to muscle, the vaginal masses were uniformly isointense on T1-weighted images, heterogeneously hyperintense on T2-weighted images and heterogeneously enhancing on contrast-enhanced images. The vaginal masses were obviously hyperintense on diffusion-weighted images (b value, 800 s/mm(2)). Extravaginal invasion was observed in three children. Pelvic lymphadenopathy was noted in two children and pulmonary metastasis was found in one child.
Conclusion:
MRI may contribute in the evaluation of vaginal endodermal sinus tumors.
