Related Experiment Video
Updated: May 14, 2026

07:30
Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
Published on: March 7, 2018
Gold nanotip array for ultrasensitive electrochemical sensing and spectroscopic monitoring
Yueyue Jiang1, Fanben Meng, Dianpeng Qi
1School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, Singapore.
Small (Weinheim an Der Bergstrasse, Germany)
|January 31, 2013
Abstract:
A gold nanotip array platform with a combination of ultrasensitive electrochemical sensing and spectroscopic monitoring capability is reported. Adenosine triphosphate is detected down to 1 pM according to the impedance changes in response to aptamer-specific binding. Furthermore, the local molecular information can be monitored at the individual plasmonic nanotips, and hence provide the capability for a better understanding of complex biological processes.

