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Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

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Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
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Optical coherence tomography changes in macular CMV retinitis.

Lisa L Sun1, Todd Goodwin, Joseph J Park

  • 1Ophthalmology Department, Royal Brisbane & Women's Hospital, Herston, Queensland,        Australia.

Digital Journal of Ophthalmology : DJO
|January 31, 2013
PubMed
Summary

Cytomegalovirus (CMV) retinitis typically affects the eye periphery. This case highlights rare unilateral macular CMV retinitis in an immunosuppressed patient, with optical coherence tomography (OCT) tracking macular changes during treatment.

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Medical Imaging

Background:

  • Cytomegalovirus (CMV) retinitis commonly presents as peripheral retinal inflammation and vasculitis.
  • Macular involvement or exclusive macular necrosis is an infrequent manifestation of CMV retinitis.
  • Immunosuppression is a significant risk factor for opportunistic infections like CMV retinitis.

Purpose of the Study:

  • To report a rare case of unilateral macular Cytomegalovirus (CMV) retinitis.
  • To document the macular changes during treatment using optical coherence tomography (OCT).
  • To emphasize atypical presentations of CMV retinitis in immunocompromised individuals.

Main Methods:

  • Clinical case presentation of a 65-year-old immunosuppressed patient.
  • Diagnosis of unilateral macular CMV retinitis.
  • Serial optical coherence tomography (OCT) imaging to monitor macular status during antiviral therapy.

Main Results:

  • The patient presented with unilateral macular CMV retinitis, an unusual presentation.
  • Optical coherence tomography (OCT) revealed specific changes within the macula.
  • Treatment led to documented modifications in the macular pathology as observed via OCT.

Conclusions:

  • Macular CMV retinitis can occur as a rare, unilateral presentation in immunosuppressed patients.
  • Optical coherence tomography (OCT) is valuable for monitoring treatment response and disease progression in macular CMV retinitis.
  • Awareness of atypical CMV retinitis presentations is crucial for timely diagnosis and management.