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[Impact of multifactor intensive intervention on self management, risk factor control and outcome of post
Ya-ping He1, Zhi-gang Lu, Yong-wen Gu
1Division of Cardiology, Shanghai 6th Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China.
Insights
Intensive intervention improves secondary prevention for patients after percutaneous coronary intervention (PCI). This multifactor approach enhances self-management and risk factor control, leading to better outcomes and fewer cardiovascular events.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Preventive Cardiology
Context:
- Post-percutaneous coronary intervention (PCI) patients require comprehensive management for secondary prevention.
- Standard care may not adequately address self-management and risk factor control in these patients.
- Optimizing care pathways is crucial for improving long-term outcomes in coronary heart disease (CAD).
Purpose:
- To evaluate the efficacy of a multifactor intensive intervention program for outpatients following PCI.
- To assess the impact of the intervention on patient self-management, risk factor control, and clinical outcomes.
- To compare the intensive intervention group with a usual care group over a 12-month follow-up period.
Summary:
- A randomized trial involving 263 post-PCI patients compared intensive intervention with usual care.
- The intensive group received frequent outpatient visits, telephone instructions, and optimal medication, alongside CAD lectures.
- Significant improvements were observed in LDL-C control, adherence to lifestyle modifications (diet, exercise), and medication use (beta-blockers, statins) in the intensive group.
Impact:
- The intensive intervention significantly reduced the rate of cardiovascular events compared to usual care (0% vs. 5.9%).
- Improved lipid profiles (LDL-C < 2.6 mmol/L) were achieved in 71.2% of the intensive group versus 48.3% in the usual care group.
- This multifactor approach demonstrates substantial benefits for secondary prevention in post-PCI patients, enhancing adherence and clinical results.
Objective:
To test the efficacy of multifactor intensive intervention for post percutaneous transluminal coronary intervention (post-PCI) outpatients on self management, risk factor control and outcome.
Methods:
A total of 263 patients with coronary heart disease (CAD) discharged from our cardiac center were randomized into usual care (4 CAD lectures focusing on the 2(nd) CAD prevention and patients-oriented outpatient visit) and intensive intervention (4 CAD lectures focusing on the 2(nd) CAD prevention, CAD outpatient visit twice a month, monthly telephone instructions on risk factor control and optimal medication). Patients were followed for 12 months and 250 patients completed follow-up.
Results:
There were more patients achieved a LDL-C level of less than 2.6 mmol/L in intensive intervention group than in usual care group (71.2% vs. 48.3%, P < 0.01). The percentages of patients taking dietary control (55.3% vs. 26.2%, P < 0.01) and physical exercises (64.4% vs. 39.0%, P < 0.01), receiving beta-adrenergic receptor blocker (75.0% vs. 50.8%, P < 0.01) and statins (72.0% vs. 54.2%, P < 0.01) were significantly higher while cardiovascular event rate (5.9% vs. 0%, P = 0.005)was significantly lower in intensive intervention group than in usual care group.
Conclusion:
Multifactor intensive intervention is helpful on improving the second prevention for post-PCI coronary heart disease patients.
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