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Related Experiment Video

Updated: May 14, 2026

An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment

An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment

Published on: July 28, 2012

Real-time bladder lesion registration and navigation: a phantom study.

Michelle Agenant¹, Herke-Jan Noordmans, Wim Koomen

¹Department of Urology, University Medical Centre Utrecht, Utrecht, The Netherlands. m.agenant@umcutrecht.nl

|February 1, 2013

Summary

A new bladder navigation system improves cystoscopy accuracy for bladder cancer. This system aids in lesion registration and navigation, potentially reducing high recurrence rates in bladder cancer patients.

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Area of Science:

Urology
Medical Imaging
Surgical Navigation

Background:

Bladder cancer is a common malignancy in men with high recurrence rates (33-64%).
Current cystoscopy tumor documentation is suboptimal, potentially contributing to high recurrence rates.

Purpose of the Study:

To develop a bladder registration and navigation system.
To enhance bladder tumor documentation and cystoscopy reproducibility.

Main Methods:

A stereo-tracker and specialized software were used to register the 3D position of bladder lesions.
Navigational cues were displayed to guide endoscopists to registered lesions.
System accuracy was tested using bladder phantoms, evaluating calibration, camera types, and volume changes.

Main Results:

The bladder registration and navigation system demonstrated acceptable accuracy for lesion registration and navigation.
Bladder volume changes and deformation were identified as limitations.
System accuracy was not significantly limited by using a previously saved calibration.

Conclusions:

The developed system offers a promising tool for improving cystoscopy reproducibility in urological practice.
Further in vivo studies are necessary to assess the system's effectiveness and limitations in clinical settings.
Addressing limitations like bladder volume changes is crucial for optimal performance.