[Hyperbaric oxygenation in the combined therapy of glomerulonephritis]

As many as 51 patients afflicted with glomerulonephritis were examined. Of these, 26 received multimodality treatment including hyperbaric oxygenation (HBO) sessions. The efficacy of the multimodality treatment was assessed from the totality of the clinico-biochemical parameters, measurements of the activity of lipid peroxidation, appraisal of the condition of the antioxidant body systems, the activity of A2 phospholipase and the lipid phase of erythrocytic membranes. The studies performed have demonstrated the clinical efficacy of HBO as well as positive changes in the structure of the lipid phase of cell membranes. To prevent unfavourable effects of HBO, it is suggested that the level of alpha-tocopherol in cell membranes should be controlled and the intake of the drugs potentiating the hyperoxic effect should be restricted.