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Updated: May 14, 2026
Generation and Quantitative Analysis of Pulsed Low Frequency Ultrasound to Determine the Sonic Sensitivity of Untreated and Treated Neoplastic Cells
Published on: July 22, 2015
Quantitative ultrasound visualization of cell death: emerging clinical applications for detection of cancer treatment
Ali Sadeghi-Naini1, Omar Falou, Gregory J Czarnota
1Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada. Ali.Sadeghi-Naini@sunnybrook.ca
Abstract:
Differentiable echogeneities exhibited by living and dead cells enables the monitoring of cell death response via quantitative ultrasound techniques at high-frequencies and recently at clinical range frequencies. Such capability can be potentially employed to provide rapid and quantitative functional information in real time, and at the patient bedside for evaluating therapy response early following treatment. This paper summarizes backgrounds on quantitative ultrasound visualization of cell death and highlights its potential capabilities for monitoring cancer treatment response, where favorable results have been reported, according to a recent pilot clinical study.
