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Updated: May 14, 2026

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SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments
Published on: August 8, 2025
Psoriasis segmentation through chromatic regions and Geometric Active Contours
F Bogo1, M Samory, A Belloni Fortina
1Dip. Ing. Informazione, Univ. Padova.
Summary
We developed a new method to segment psoriasis lesions in full-body photos. This algorithm accurately identifies and outlines numerous lesions, matching human operator consistency for psoriasis segmentation.
Area of Science:
- Dermatology
- Medical Image Analysis
- Computer Vision
Background:
- Psoriasis is a chronic skin condition requiring accurate lesion measurement.
- Manual segmentation of numerous psoriasis lesions in digital images is time-consuming and subjective.
Purpose of the Study:
- To develop and validate an automated algorithm for segmenting psoriasis lesions in full-body digital photographs.
- To compare the algorithm's segmentation performance against human operators.
Main Methods:
- A novel algorithm combining chromatic information for initial lesion zone identification.
- Utilizing Geometric Active Contours for precise plaque segmentation.
- Evaluation of segmentation variability against multiple human operators.
Main Results:
- The algorithm successfully isolates and segments psoriasis plaques from full-body images.
- The segmentation variability of the algorithm is comparable to the variability observed between human operators.
- The approach is effective even with a large number of discrete lesions.
Conclusions:
- The proposed automated method offers a reliable and consistent approach for psoriasis lesion segmentation.
- This algorithm has the potential to improve the efficiency and objectivity of psoriasis assessment in clinical and research settings.
- The developed technique demonstrates performance on par with human expert segmentation.

