[Antibacterial agent Oftaquix efficacy in cataract phacoemulsification].

Area of Science:

• Ophthalmology
• Microbiology
• Clinical Pharmacology

Background:

• Cataract surgery, specifically phacoemulsification with intraocular lens (IOL) implantation, carries a risk of post-operative bacterial infection.
• Pre-operative antibiotic prophylaxis is crucial for minimizing infection rates in ophthalmic procedures.

Purpose of the Study:

• To evaluate the efficacy of Oftaquix as a pre-operative antibacterial agent in patients undergoing cataract phacoemulsification with IOL implantation.
• To assess the duration and stability of the antibacterial effect of Oftaquix.

Main Methods:

• A clinical study involving patients undergoing cataract surgery.
• Administration of Oftaquix two days prior to surgery.
• Bacteriological analysis of conjunctival cavity samples on the day of surgery and 19-21 days post-surgery.
• Comparison of bacterial growth rates between an experimental group (Oftaquix) and a control group.

Main Results:

• Oftaquix administration effectively eliminated bacterial agents from the conjunctival cavity by the day of surgery.
• A significant and stable antibacterial effect was observed.
• Bacterial growth was detected in only 6.7% of patients in the Oftaquix group compared to 30% in the control group at 19-21 days post-surgery.

Conclusions:

• Pre-operative use of Oftaquix is effective in eradicating bacteria from the conjunctival sac before cataract surgery.
• Oftaquix demonstrates a significant and sustained antibacterial effect, reducing the incidence of post-operative bacterial growth in patients undergoing phacoemulsification with IOL implantation.