Related Experiment Video
Updated: May 14, 2026

Reconstitution of Septin Assembly at Membranes to Study Biophysical Properties and Functions
Published on: July 28, 2022
Squaring, parity breaking, and S tumbling of vesicles under shear flow
Alexander Farutin1, Chaouqi Misbah
1Laboratoire Interdisciplinaire de Physique, UMR5588, Université Grenoble I CNRS, Grenoble F-38041, France. alexandr.farutin@ujf-grenoble.fr
Abstract:
The numerical study of 3D vesicles with a reduced volume equal to that of human red blood cells leads to the discovery of three types of dynamics: (i) squaring motion, in which the angle between the direction of the longest distance and the flow velocity undergoes discontinuous jumps over time, (ii) spontaneous parity breaking of the shape leading to cross-streamline migration, and (iii) S tumbling where the vesicle tumbles, exhibiting a pronounced S-like shape with a waisted morphology in the center. We report on the phase diagram within a wide range of relevant parameters. Our estimates reveal that healthy and pathological red blood cells are also prone to these types of motion, which may affect blood microcirculation and impact oxygen transport.
More Related Videos
10:08Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy
Published on: October 24, 2017
09:29Obtention of Giant Unilamellar Hybrid Vesicles by Electroformation and Measurement of their Mechanical Properties by Micropipette Aspiration
Published on: January 19, 2020
Related Concept Videos
Pinching-off of Coated Vesicles
SNAREs and Membrane Fusion
SNAREs exist in pairs that symmetrically interact and catalyze the fusion of the lipid bilayers in vesicle and target organelle. v-SNARE in the vesicle membrane are single polypeptide chains that bind to a complementary t-SNARE, composed of 2...
Vesicular Tubular Clusters
With the help of motor proteins such...
Problem Solving on Stress and Strain