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Maxillary rhinosinusitis due to Fusarium species leading to cavernous sinus thrombosis

V S Rajmane1, S T Rajmane, V C Patil

  • 1Department of Microbiology, KIMSU, Karad, 415110 Maharashtra, India. drvsrajmane@yahoo.com

Journal De Mycologie Medicale
|February 2, 2013
PubMed

Insights

Fungal sinusitis, a growing concern, can lead to severe complications. This case highlights Fusarium sinusitis causing rare cavernous sinus thrombosis, successfully treated with amphotericin B.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Neurology

Background:

  • Fungal rhinosinusitis is increasingly reported globally.
  • Intracranial complications of fungal sinusitis carry high mortality risks.
  • Fusarium species are emerging pathogens in invasive fungal infections.

Observation:

  • A 55-year-old diabetic male presented with chronic left maxillary sinusitis.
  • Diagnosis revealed cavernous sinus thrombosis secondary to Fusarium species infection.
  • Microscopic examination and culture confirmed Fusarium sinusitis.

Findings:

  • Direct microscopic examination of sinus lavage showed fungal elements.
  • Culture identified Fusarium species within 4 days.
  • Intravenous amphotericin B therapy led to a favorable outcome.

Implications:

  • This case underscores the potential for rare, severe complications like cavernous sinus thrombosis from Fusarium sinusitis.
  • Early diagnosis and prompt treatment with antifungal agents are crucial for managing invasive fungal sinusitis.
  • Highlights the need for increased awareness of fungal sinusitis and its intracranial extensions in clinical practice.

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