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The Melbourne Diabetes Prevention Study (MDPS): study protocol for a randomized controlled trial.

Nathalie Davis-Lameloise¹, Andrea Hernan, Edward D Janus

¹Greater Green Triangle University Department of Rural Health, Flinders University and Deakin University, PO Box 423, Warrnambool, VIC 3280, Australia.

|February 2, 2013

Summary

This summary is machine-generated.

This study evaluates the Life! program to prevent type 2 diabetes (T2DM) in high-risk Australians. The intervention aims to reduce central obesity and cardiovascular risks, potentially lowering T2DM incidence.

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Area of Science:

Public Health
Preventive Medicine
Clinical Trials

Background:

Type 2 diabetes (T2DM) prevalence is rising globally and is a significant health burden in Australia.
Lifestyle modification programs are effective in reducing T2DM incidence in high-risk individuals.
The 'Life! Taking action on diabetes' program is based on successful international and Australian trials.

Purpose of the Study:

To evaluate the effectiveness of a specific version of the 'Life!' program in preventing T2DM.
To assess the cost-effectiveness of the intervention compared to usual care.
To determine the intervention's impact on central obesity and cardiovascular risk factors.

Main Methods:

An open randomized clinical trial recruiting 796 participants aged 50-75 years.
Participants screened using AUSDRISK; those with diabetes excluded.
Intervention group receives structured group sessions based on the Health Action Process Approach (HAPA) model; control group receives usual care.
Anthropometric, laboratory tests, and surveys conducted at baseline, 3 months (intervention group only), and 12 months.

Main Results:

This section is not available in the provided abstract.

Conclusions:

The study will determine if the intervention effectively reduces central obesity and cardiovascular risk factors.
It will compare the economic impact of the intervention against usual care.
Findings will inform diabetes prevention strategies in Australia.