Related Experiment Videos
Solid and papillary neoplasm arising from an ectopic pancreas in the mesocolon
O Ishikawa1, S Ishiguro, H Ohhigashi
1Department of Surgery, Center for Adult Diseases, Osaka, Japan.
The American Journal of Gastroenterology
|May 1, 1990
Summary
This report details a rare case of a solid and papillary neoplasm arising from an ectopic pancreas in a young girl. The tumor, successfully resected, showed unique histological features and pancreatic tissue components.
Area of Science:
- Gastroenterology and Surgical Oncology
- Pediatric Pathology
Background:
- Ectopic pancreas, pancreas tissue found outside its normal location, is a rare congenital anomaly.
- Solid and papillary neoplasm of the pancreas (SPN) is an uncommon, typically low-grade malignant tumor primarily affecting young women.
Observation:
- A case of a 13-year-old girl with an 8-cm, encapsulated, partially calcified tumor protruding from the mesocolon is presented.
- Histological examination revealed a solid and papillary neoplasm with uniformly small cells positive for alpha 1-antitrypsin, suggesting acinar cell differentiation.
- Associated ectopic pancreatic tissue, including islet, acinar, and ductular cells, was identified within the mesocolon at the tumor base.
Findings:
- The tumor exhibited histological characteristics of a solid and papillary neoplasm.
- The presence of zymogen-like granules indicated acinar cell differentiation within the neoplasm.
- This case represents the first documented instance of a solid and papillary neoplasm originating from a mesocolonic ectopic pancreas.
Implications:
- This finding expands the known spectrum of tumors associated with ectopic pancreatic tissue.
- Highlights the importance of considering rare pancreatic neoplasms in pediatric patients with abdominal masses.
- Contributes to the understanding of pancreatic tumor development in extragastric locations.