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Updated: May 14, 2026

An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment

An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment

Published on: July 28, 2012

Vaginal brenner tumor.

Ruthy Shaco-Levy¹, Daniel Benharroch

¹Department of Pathology, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. rsl@bgu.ac.il

International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists

|February 2, 2013

Summary

This summary is machine-generated.

Extraovarian Brenner tumors are very rare. This case report describes a vaginal Brenner tumor in an 84-year-old woman, suggesting a metaplastic origin from the müllerian epithelium.

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Area of Science:

Gynecologic Pathology
Oncology

Background:

Extraovarian Brenner tumors are exceptionally rare.
Brenner tumors are typically found in the ovary.

Observation:

A case of a vaginal Brenner tumor was identified in an 84-year-old female.
The tumor presented as a 1.8-cm polypoid mass in the lower vagina, causing vulvar irritation.
Microscopic examination revealed characteristic features: urothelial islands, glands, and fibrous stroma.

Findings:

The vaginal mass exhibited the classic histological components of a Brenner tumor.
This represents a rare instance of a vaginal Brenner tumor, distinct from ovarian origins.

Implications:

The findings suggest a potential metaplastic origin of vaginal Brenner tumors from the müllerian epithelium.
This case expands the understanding of the differential diagnosis for vaginal masses and rare gynecologic tumors.