Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Standard Precaution01:26

Standard Precaution

Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Techniques of therapeutic communication I: Active Listening, Sharing Observations, Validation, and Using Touch01:15

Techniques of therapeutic communication I: Active Listening, Sharing Observations, Validation, and Using Touch

The history of therapeutic communication can be traced back to Florence Nightingale, who emphasized the importance of developing trusting relationships with patients. She taught that the presence of nurses with patients results in therapeutic healing.
Therapeutic communication is not the same as social interaction. Social interaction has no goal or purpose and consists of casual information sharing, whereas therapeutic communication has a plan or purpose for the conversation. Therapeutic...
Sample Handling01:02

Sample Handling

Transportation of samples from the collection point to the laboratory, as well as storage and preservation techniques, are crucial for maintaining sample integrity and ensuring accurate and reliable test results.
Samples should be transported carefully from collection points to the laboratory. They should be properly sealed and clearly labeled to prevent cross-contamination. To preserve the sample integrity, optimal temperature conditions during transport are essential. This could involve using...
Hand hygiene01:23

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
PPE Use in Healthcare Settings II: Doffing01:10

PPE Use in Healthcare Settings II: Doffing

The sequence of removing or doffing PPE starts with the gloves, as they are the most contaminated. Next is removal of the face shield or goggles, as they would interfere with removing other PPE. Then remove the gown, followed by the mask or respirator. Perform hand hygiene between steps if hands become contaminated and immediately after removing all PPE. Generally, the outside front and sleeves of the isolation gown, the goggles or the mask, the respirator, and the face shield are contaminated.
Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A model to increase automation and support reliable interpretation of clinical chemistry tests.

Clinical chemistry and laboratory medicine·2026
Same author

Thyroglobulin as a proxy for iodine status in pregnancy.

The British journal of nutrition·2026
Same author

ULK4 and CDKN2A polymorphisms influence the risk of developing monoclonal gammopathy of undetermined significance.

International journal of cancer·2026
Same author

Correction: Ketogenic diet improves disease activity and cardiovascular risk in psoriatic arthritis: A proof of concept study.

PloS one·2026
Same author

Flow cytometry, cytology and histology in the diagnosis of ocular hematologic neoplasms: a 15-year monocentric experience with a focus on ocular lymphomas.

Clinical chemistry and laboratory medicine·2025
Same author

Myocardial damage in a 4-year old who ingested bisoprolol and hydrochlorothiazide - Incidental CK-BB highlighted other tissue toxicity.

Clinical biochemistry·2025

Related Experiment Video

Updated: May 14, 2026

Fertility Preservation in Patients with Severe Ovarian Dysfunction
12:03

Fertility Preservation in Patients with Severe Ovarian Dysfunction

Published on: March 25, 2021

CA 19-9: handle with care.

Claudio Galli1, Daniela Basso, Mario Plebani

  • 1Scientific Affairs, Abbott Diagnostics Division, Rome, Italy.

Clinical Chemistry and Laboratory Medicine
|February 2, 2013
PubMed
Summary
This summary is machine-generated.

Carbohydrate antigen 19-9 (CA 19-9) is useful for monitoring pancreatic and gastrointestinal cancers, but not recommended for screening due to limited sensitivity and specificity.

More Related Videos

Automatic Separation and Collection of Cancer-Related Substances from Clinical Samples
08:49

Automatic Separation and Collection of Cancer-Related Substances from Clinical Samples

Published on: January 13, 2023

Quantitation of Protein Expression and Co-localization Using Multiplexed Immuno-histochemical Staining and Multispectral Imaging
08:40

Quantitation of Protein Expression and Co-localization Using Multiplexed Immuno-histochemical Staining and Multispectral Imaging

Published on: April 8, 2016

Related Experiment Videos

Last Updated: May 14, 2026

Fertility Preservation in Patients with Severe Ovarian Dysfunction
12:03

Fertility Preservation in Patients with Severe Ovarian Dysfunction

Published on: March 25, 2021

Automatic Separation and Collection of Cancer-Related Substances from Clinical Samples
08:49

Automatic Separation and Collection of Cancer-Related Substances from Clinical Samples

Published on: January 13, 2023

Quantitation of Protein Expression and Co-localization Using Multiplexed Immuno-histochemical Staining and Multispectral Imaging
08:40

Quantitation of Protein Expression and Co-localization Using Multiplexed Immuno-histochemical Staining and Multispectral Imaging

Published on: April 8, 2016

Area of Science:

  • Oncology
  • Clinical Chemistry
  • Biomarker Research

Background:

  • Carbohydrate antigen 19-9 (CA 19-9) testing was introduced in the mid-1980s for cancer diagnosis and monitoring.
  • CA 19-9 has demonstrated utility as a prognostic indicator and monitoring tool for specific malignancies.

Purpose of the Study:

  • To review fundamental concepts of CA 19-9 testing.
  • To evaluate current applications of CA 19-9, focusing on recent evidence.
  • To analyze assay interference, method comparisons, and monitoring of malignant diseases.

Main Methods:

  • Literature review of existing evidence on CA 19-9 testing.
  • Focus on recent studies concerning assay interference and method comparisons.
  • In-depth analysis of prognostic value and monitoring recommendations for specific cancers.

Main Results:

  • CA 19-9 is validated for monitoring pancreatic and gastrointestinal cancers.
  • Concerns exist regarding CA 19-9's diagnostic accuracy due to insufficient sensitivity and specificity.
  • Screening applications of CA 19-9 are not recommended.

Conclusions:

  • CA 19-9 remains a valuable prognostic and monitoring tool for pancreatic, gastric, and colorectal cancers.
  • Limitations in sensitivity and specificity impact its use in diagnosis and preclude its use in screening.
  • Continued research into assay interference and method standardization is crucial.