[Pathomechanisms of myasthenic crisis states]

From the point of view of the kind of fate of those people ill with myasthenia the crisis itself can be regarded as the most dangerous and usually the most problematic phenomenon. To the crisis belong all those conditions characteristic of serious respiratory failure and those occurring either as a direct result of myasthenia or due to other causes associated with other illnesses. Clinically, there are three main kinds of crisis: myasthenic, cholinergic, and oscillatory/,brittle". There is the possibility of 3 directions of study on the crisis: The careful analysis, coordination, and observation of the clinical picture, with precise notation of the course of the illness. Analysis of the neuro-muscular types of blockade which occur in myasthenia. Interpretation of changes such as resistance and intolerance observed during the process and which conform to the pathomechanism. The author deals with problems mentioned with regard to his casuistry of 300 people ill with myasthenia.