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Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
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Appendicitis01:19

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Updated: May 14, 2026

A Coregistered Ultrasound and Photoacoustic Imaging Protocol for the Transvaginal Imaging of Ovarian Lesions
10:21

A Coregistered Ultrasound and Photoacoustic Imaging Protocol for the Transvaginal Imaging of Ovarian Lesions

Published on: March 3, 2023

Daughter cyst sign.

William Thoburn Randazzo1, Arie Franco, Saudiqa Hoossainy

  • 1Department of Radiology, Georgia Health Sciences University, Augusta, Georgia, USA.

Journal of Radiology Case Reports
|February 2, 2013
PubMed
Summary
This summary is machine-generated.

The daughter cyst sign indicates a simple ovarian cyst, not an ectopic pregnancy. This case highlights a rare instance in a young McCune-Albright syndrome patient.

Keywords:
Daughter cystectopic pregnancyovarian cystovarian follicle

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Published on: July 25, 2017

Area of Science:

  • Reproductive endocrinology
  • Pediatric radiology
  • Gynecologic pathology

Background:

  • The daughter cyst sign is a specific sonographic finding for uncomplicated ovarian cysts.
  • It is crucial to differentiate ovarian cysts from ectopic pregnancies in reproductive-aged individuals.
  • McCune-Albright syndrome is associated with precocious puberty, leading to early ovarian follicular development.

Observation:

  • A 3-year-old female with McCune-Albright syndrome presented with symptoms mimicking ectopic pregnancy.
  • Sonography revealed an uncomplicated ovarian cyst exhibiting the daughter cyst sign.
  • This finding was initially concerning for ectopic pregnancy due to the patient's precocious puberty.

Findings:

  • The daughter cyst sign was definitively identified, confirming an uncomplicated ovarian cyst.
  • The patient's presentation, despite precocious puberty, did not involve an ectopic pregnancy.
  • This case underscores the importance of considering benign gynecologic conditions even in the presence of hormonal abnormalities.

Implications:

  • Accurate sonographic interpretation is vital for differentiating benign ovarian cysts from emergent conditions like ectopic pregnancy.
  • Understanding the spectrum of findings in McCune-Albright syndrome is essential for appropriate clinical management.
  • This case expands the differential diagnosis for the daughter cyst sign in pediatric patients with hormonal imbalances.