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Updated: May 14, 2026

Characterization of Intra-Cartilage Transport Properties of Cationic Peptide Carriers
Published on: August 10, 2020
Abstract:
Many transport proteins, especially organic anion transporters, assist the entry of several substances into cells. Their specific roles remain poorly understood. Transporters located in the gut can increase the plasma concentrations of their substrate drugs. In contrast, transporters located in the renal tubular epithelium ultimately lead to lower plasma concentrations of their substrate drugs. Several drugs inhibit specific transport systems. The efficiency of these transport proteins varies widely between individuals, meaning that the clinical severity of the drug interactions in which they play a role is rather unpredictable.
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