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A case of pityriasis rubra pilaris associated with membranous nephropathy

Chin-Yun Lin1, Paul D L Maurice, Nick B Cross

  • 1Departments of Dermatology Nephrology, Canterbury District Health Board, Christchurch, New Zealand. cyf.trust@gmail.com

The Australasian Journal of Dermatology
|February 5, 2013
PubMed

Insights

Pityriasis rubra pilaris (PRP), a rare skin condition, was found to be associated with membranous nephropathy (MN), a kidney disease. The conditions resolved together, suggesting a potential link between PRP and kidney disorders.

Area of Science:

  • Dermatology and Nephrology
  • Rare autoimmune-related dermatoses
  • Renal disease associations with skin conditions

Background:

  • Pityriasis rubra pilaris (PRP) is a rare idiopathic inflammatory skin disorder.
  • PRP is occasionally linked to autoimmune conditions, HIV, and malignancies.
  • Associations between PRP and renal diseases are infrequently documented.

Observation:

  • This report details a patient with Pityriasis rubra pilaris (PRP).
  • The patient also presented with membranous nephropathy (MN), a form of kidney disease.
  • The PRP and MN resolved concurrently.

Findings:

  • This case represents the second reported instance of Pityriasis rubra pilaris (PRP) associated with membranous nephropathy (MN).
  • The spontaneous resolution of both dermatosis and nephropathy suggests a potential etiological connection.
  • The co-occurrence highlights an underrecognized association between PRP and renal pathology.

Implications:

  • Further case reports are needed to establish a definitive link between PRP and MN.
  • Investigating this association may provide insights into the pathogenesis of both Pityriasis rubra pilaris and membranous nephropathy.
  • This case underscores the importance of considering renal involvement in patients with PRP.

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