Related Experiment Videos
Superoxide dismutase-like activity of 1,2,3-triazole derivatives
G Biagi1, O Livi, G L Ramacciotti
1Istituto di Chimica Farmaceutica e Tossicologica, Università di Pisa.
Farmaco (Societa Chimica Italiana : 1989)
|January 1, 1990
Abstract:
This paper reports the synthesis of some sulfurated 1,2,3-triazole derivatives and the biological evaluation, for the superoxide dismutase-like activity, of these new compounds together with several 1,2,3-triazoles previously described by us. All the compounds possess a SOD-like activity and some of them showed an activity equivalent to or higher than those of penicillamine or thiopronin, which are well known therapeutic drugs in the treatment of rheumatoid arthritis.