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Related Experiment Video

Updated: May 14, 2026

Translational Orthotopic Models of Glioblastoma Multiforme
07:37

Translational Orthotopic Models of Glioblastoma Multiforme

Published on: February 17, 2023

Cervical metastatic glioblastoma multiforme.

Syeddah Shafaq Mujtaba1, Saroona Haroon, Naveen Faridi

  • 1Department of Histopathology, Liaquat National Postgraduate Medical Institute, Karachi.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|February 5, 2013
PubMed
Summary

Extracranial spread of glioblastoma multiforme (GBM), a malignant brain tumor, is uncommon but increasing. This case highlights cervical metastasis, discussing potential mechanisms of extraneural spread.

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Area of Science:

  • Neuro-oncology
  • Pathology
  • Surgical Oncology

Background:

  • Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor in adults.
  • Despite its aggressive nature, extracranial metastasis of GBM is rare.
  • Improved treatments are leading to increased survival, with a rise in reported extracranial GBM occurrences.

Observation:

  • Common sites for GBM extracranial metastasis include lungs, lymph nodes, neck, skull, scalp, liver, and bones.
  • Head and neck metastases can significantly impact patient quality of life.
  • This report details a specific case of cervical metastasis from GBM.

Findings:

  • Extracranial spread of GBM, while infrequent, is an emerging clinical observation.
  • Cervical metastasis presents a significant challenge in managing GBM patients.

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Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells
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Last Updated: May 14, 2026

Translational Orthotopic Models of Glioblastoma Multiforme
07:37

Translational Orthotopic Models of Glioblastoma Multiforme

Published on: February 17, 2023

Tumor Treating Field Therapy in Combination with Bevacizumab for the Treatment of Recurrent Glioblastoma
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Tumor Treating Field Therapy in Combination with Bevacizumab for the Treatment of Recurrent Glioblastoma

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Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells
12:52

Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells

Published on: November 28, 2015

  • The study explores potential pathways for GBM's extraneural dissemination.

    • Implications:

    • Understanding GBM's metastatic potential is crucial for comprehensive patient care.
    • Early detection of extracranial spread can inform treatment strategies.
    • Further research into GBM's metastatic mechanisms may reveal novel therapeutic targets.