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Updated: May 14, 2026

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Harnessing the Bioorthogonal Inverse Electron Demand Diels-Alder Cycloaddition for Pretargeted PET Imaging
Published on: February 3, 2015
Potent and selective tariquidar bioisosters as potential PET radiotracers for imaging P-gp
Marialessandra Contino1, Laura Zinzi, Maria Grazia Perrone
1Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari 'A. Moro', via Orabona, 4, 70125 Bari, Italy.
Bioorganic & Medicinal Chemistry Letters
|February 5, 2013
Abstract:
Compounds 8a-d have been designed as bioisosters of tariquidar for imaging P-gp expression and density by PET. The results displayed that compounds 8b and 8d could be considered potential P-gp/BCRP ligands suitable as (11)C and (18)F radiotracers, respectively.
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