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Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

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Related Experiment Video

Updated: May 14, 2026

Targeted and Selective Treatment of Pluripotent Stem Cell-derived Teratomas Using External Beam Radiation in a Small-animal Model

Targeted and Selective Treatment of Pluripotent Stem Cell-derived Teratomas Using External Beam Radiation in a Small-animal Model

Published on: February 17, 2019

Radiation-induced angiosarcoma.

C Lane Anzalone¹, Philip R Cohen, Abdul H Diwan

¹Medical School, University of Texas at Houston School of Medicine, Houston, TX, USA.

Dermatology Online Journal

|February 5, 2013

Summary

This summary is machine-generated.

Radiation-induced angiosarcomas are rare but serious complications. Prompt biopsy of new skin lesions in radiation fields is crucial for early detection and effective management of these tumors.

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Last Updated: May 14, 2026

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Area of Science:

Oncology
Dermatology
Medical Imaging

Background:

Radiation-induced angiosarcomas are rare but serious complications following cancer treatment.
Early diagnosis and prompt management are critical for improving patient outcomes.

Observation:

This case study describes the clinical characteristics of radiation-induced angiosarcomas.
The condition typically manifests within the radiation field, approximately six years post-treatment.

Findings:

A review of approximately one hundred diagnosed cases was conducted.
The study highlights a patient's significant response to neoadjuvant chemotherapy (gemcitabine and docetaxel) and adjuvant chemotherapy (gemcitabine, docetaxel, ifosfamide, and adriamycin).

Implications:

New skin lesions within or adjacent to radiation ports warrant consideration for biopsy.
Sampling multiple sites for larger or ill-defined lesions is recommended to ensure accurate diagnosis and avoid false negatives.