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Effect of BN 52021, a platelet activating factor antagonist, on dithranol-induced inflammation
1Department of Dermatology, Albert Szent-Györgyi Medical University, Szeged, Hungary.
The British Journal of Dermatology
|April 1, 1990
Abstract:
The effect of BN 52021, a selective platelet activating factor (PAF) antagonist was studied on dithranol-induced irritant dermatitis. Pretreatment of the skin with 0.45% BN 52021 ointment significantly suppressed the decrease in capillary resistance, rise in skin temperature and increase in skin-fold thickness produced by dithranol.