Liver transplantation in patients infected with gram-negative bacteria: non-Acinetobacter baumannii and Acinetobacter
1Department of Liver Transplantation, Changhua Christian Hospital, Changhua, Taiwan.
Background:
The current study investigated risk factor related to gram-negative bacterial (GNB) infection by Acinetobacter baumannii and non-A baumannii groups, in liver transplantation (OLT) recipients.
Materials And Methods:
All patients with OLT and their living donors were analyzed retrospectively. After excluding those with Gram-positive and fungal infections 89 patients remained in the study including 59 who were noninfected and 30 with GNB infection. The risk factors for GNB infection were classified into the preoperative versus the postoperative periods.
Results:
GNB-infected patients were classified as non-A baumannii versus A baumannii (15 patients per group). A significant difference was observed in the numbers of intensive care and hospitalized days, hemodialysis requirement, and reoperation frequency compared with the noninfected group. Infection also correlated with hospital mortality, overall survival, and Model for End-Stage Liver Disease (MELD) scores with significance upon univariate but only the last feature on multivariate analysis.
Conclusions:
Preoperative MELD scores were more likely to be higher among the non-A baumannii compared with the A baumannii-infected group. However, the 1-year survival of the A baumannii-infected subjects was lower than that of the non-A baumannii infected group.
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