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Basal cell carcinoma with hepatic metastases
K R Postlethwaite1, D J Courtney, J R Gosney
1Glan Clwyd Hospital, Bodelwyddan, North Wales.
The British Journal of Oral & Maxillofacial Surgery
|April 1, 1990
Summary
Metastatic basal cell carcinoma (BCC) risk factors include long-standing, locally invasive facial tumors, especially metatypical subtypes. This case highlights these factors, leading to liver metastasis.
Area of Science:
- Dermatology
- Oncology
Background:
- Basal cell carcinoma (BCC) is the most common skin cancer.
- Metastasis from BCC is rare but can occur.
Observation:
- A case of advanced basal cell carcinoma (BCC) is presented.
- The primary tumor was present for over 20 years.
- It was located on the middle third of the face, locally invasive to bone, and resistant to treatment.
Findings:
- The BCC was histologically classified as a metatypical subtype.
- Several risk factors for metastasis were identified: long duration, facial location, local invasiveness, and incomplete eradication.
- The patient developed liver metastasis.
Implications:
- Understanding BCC risk factors is crucial for early detection and management.
- Metatypical BCC subtypes may warrant closer monitoring for metastatic potential.
- This case underscores the importance of aggressive treatment for high-risk BCCs.