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Updated: May 14, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
[Streptococcus intermedius: a rare cause of brain abscess in children]
1Service de pédiatrie infectieuse et d'immunologie clinique, hôpital d'Enfants de Casablanca, CHU Ibn Rochd, 20000 Casablanca, Maroc.
Abstract:
Streptococcus intermedius is a member of the Streptococcus anginosus group, also known as the Streptococcus milleri group. Although this is a commensal agent of the mouth and upper airways, it has been recognized as an important pathogen in the formation of abscesses. However, it has rarely been involved in the formation of brain abscess in children. We report 4 pediatric cases of brain abscess caused by S. intermedius. Three boys and 1 girl, all aged over 2 years, were admitted for a febrile meningeal syndrome and seizures, caused by a S. intermedius brain abscess. Diagnosis was obtained by brain imaging combined with culture of cerebrospinal fluid. The outcome was favorable after antibiotic therapy and abscess puncture. S. intermedius should be considered a potential pathogen involved in the development of brain abscess in children.
Insights
Streptococcus intermedius, a common commensal, can cause brain abscesses in children. This study highlights four pediatric cases, emphasizing early diagnosis and treatment for favorable outcomes.
Area of Science:
- Pediatric Neurology
- Infectious Diseases
- Microbiology
Background:
- Streptococcus intermedius belongs to the Streptococcus anginosus group, typically a commensal organism.
- While known for abscess formation, its role in pediatric brain abscesses is infrequent.
Observation:
- Four pediatric cases of Streptococcus intermedius brain abscess are presented.
- Patients, over 2 years old, exhibited febrile meningeal syndrome and seizures.
- Diagnosis involved brain imaging and cerebrospinal fluid cultures.
Findings:
- Streptococcus intermedius was identified as the causative agent in all four pediatric brain abscess cases.
- Successful treatment involved antibiotic therapy and abscess puncture.
Implications:
- Streptococcus intermedius should be recognized as a potential pathogen in pediatric brain abscesses.
- Prompt diagnosis and intervention are crucial for positive patient outcomes.
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