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Related Experiment Video

Updated: May 14, 2026

Quantifiable and Inexpensive Cell-Free Fluorescent Method to Confirm the Ability of Novel Compounds to Chelate Iron
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Near fatal iron intoxication managed conservatively.

Jhuma Sankar1, Amelin Shukla, Rohit Khurana

  • 1Department of Pediatrics, PGIMER, Dr RML Hospital, New Delhi, India. jhumasankar@gmail.com

BMJ Case Reports
|February 5, 2013
PubMed
Summary

A pediatric case of severe elemental iron poisoning in an infant showed remarkable recovery with conservative medical management alone, avoiding the need for exchange transfusion despite critically high iron levels.

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Last Updated: May 14, 2026

Quantifiable and Inexpensive Cell-Free Fluorescent Method to Confirm the Ability of Novel Compounds to Chelate Iron
05:36

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Setup of Capillary Electrophoresis-Inductively Coupled Plasma Mass Spectrometry (CE-ICP-MS) for Quantification of Iron Redox Species (Fe(II), Fe(III))
04:48

Setup of Capillary Electrophoresis-Inductively Coupled Plasma Mass Spectrometry (CE-ICP-MS) for Quantification of Iron Redox Species (Fe(II), Fe(III))

Published on: May 4, 2020

Area of Science:

  • Pediatric Toxicology
  • Emergency Medicine
  • Clinical Case Reports

Background:

  • Elemental iron ingestion is a common cause of poisoning in children, potentially leading to severe toxicity.
  • Prompt recognition and management are crucial for favorable outcomes in pediatric iron overdose cases.

Observation:

  • An infant presented with symptoms of severe iron toxicity, including hypotension, metabolic acidosis, and irritability, following unintentional ingestion of approximately 130 mg/kg of elemental iron.
  • Serum iron levels were significantly elevated at 360 µg/dl, indicating substantial iron absorption and systemic toxicity.

Findings:

  • The infant experienced an uneventful recovery solely through conservative medical management.
  • Exchange transfusion, a potentially invasive procedure, was not required despite the high degree of iron toxicity.

Implications:

  • This case underscores the potential efficacy of conservative management in pediatric elemental iron poisoning.
  • Highlighting successful outcomes with medical management alone may guide treatment strategies and reduce the need for more aggressive interventions in similar cases.