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Updated: May 14, 2026

Lateral Root Inducible System in Arabidopsis and Maize
Published on: January 14, 2016
Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1
Zuyu Zheng1, Yongxia Guo, Ondřej Novák
1Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, California, USA.
Abstract:
We identify an Arabidopsis pyridoxal-phosphate-dependent aminotransferase, VAS1, whose loss-of-function simultaneously increases amounts of the phytohormone auxin and the ethylene precursor 1-aminocyclopropane-1-carboxylate. VAS1 uses the ethylene biosynthetic intermediate methionine as an amino donor and the auxin biosynthetic intermediate indole-3-pyruvic acid as an amino acceptor to produce L-tryptophan and 2-oxo-4-methylthiobutyric acid. Our data indicate that VAS1 serves key roles in coordinating the amounts of these two vital hormones.
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