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Brain Abscess l: Introduction01:26

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A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
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Listeria monocytogenes Infection of the Brain
05:02

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Published on: October 2, 2018

Common bacteria isolated from brain abscesses.

Fatima M Al-Rashdi1, Latifa K Al-Ismaily, Kokkuvayil L Devi

  • 1Laboratory Department, Khoula Hospital, Muscat, Sultanate of Oman. Tel. +968 565785/540770. Fax. +968 562481.

Neurosciences (Riyadh, Saudi Arabia)
|February 5, 2013
PubMed
Summary

Streptococci and Staphylococcus aureus are the main bacteria causing brain abscesses in Oman. Prompt treatment of infections like otitis media is crucial, especially in children and adolescents, to prevent this serious condition.

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Area of Science:

  • Medical Microbiology
  • Neurosurgery
  • Infectious Diseases

Background:

  • Brain abscesses are serious infections requiring prompt diagnosis and treatment.
  • Identifying causative agents is key for effective antimicrobial therapy.
  • Oman's Khoula Hospital is the sole neurosurgical center in the Sultanate.

Purpose of the Study:

  • To identify common bacteria causing brain abscesses at Khoula Hospital, Oman.
  • To analyze predisposing factors for brain abscess formation.
  • To inform targeted treatment strategies and public health awareness.

Main Methods:

  • Retrospective study of brain abscess cases from January 1999 to December 2000.
  • Review of microbiology laboratory and patient medical records.
  • Data collection from patients admitted to the Neurosurgical Department.

Main Results:

  • Thirteen brain abscess cases were identified.
  • Streptococci (53.8%) and Staphylococcus aureus (26.7%) were the predominant pathogens.
  • Otitis media was the most common associated condition, followed by sinusitis and meningitis.

Conclusions:

  • Brain abscesses are life-threatening; knowledge of etiology guides life-saving antimicrobial therapy.
  • Incidence remains high in children and adolescents.
  • Public awareness and prompt treatment of antecedent infections can reduce brain abscess incidence.