Related Experiment Videos

Chronic rhinosinusitis increased the risk of stroke: a 5-year follow-up study

Jiunn-Horng Kang1, Chuan-Song Wu, Joseph J Keller

  • 1Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, Taipei, Taiwan.

The Laryngoscope
|February 5, 2013
PubMed

Insights

Patients with chronic rhinosinusitis (CRS) face a higher risk of stroke. This population-based study found a 34% increased likelihood of ischemic stroke in CRS patients over five years.

Area of Science:

  • Neurology
  • Epidemiology
  • Otolaryngology

Background:

  • Chronic rhinosinusitis (CRS) is linked to intracranial vessel involvement and potential stroke risk.
  • The precise epidemiological profile of stroke risk in CRS patients remains unclear.

Purpose of the Study:

  • To investigate the incidence and risk of stroke in individuals diagnosed with chronic rhinosinusitis.
  • To conduct a large-scale, population-based cohort study in Taiwan to explore this association.

Main Methods:

  • Utilized the Taiwan Longitudinal Health Insurance Database for cohort retrieval.
  • Included 15,846 CRS patients and 37,538 controls, tracking them for 5 years post-diagnosis.
  • Employed stratified Cox proportional hazards regressions to compare stroke risk.

Main Results:

  • Stroke incidence was 10.65 per 100 person-years in CRS patients versus 7.53 in controls.
  • CRS patients showed a 34% higher risk of ischemic stroke (HR=1.34, 95% CI: 1.18-1.53).
  • No significant difference in subarachnoid or intracerebral hemorrhage risk was observed.

Conclusions:

  • Individuals with chronic rhinosinusitis exhibit an elevated risk of stroke.
  • The findings highlight the importance of considering stroke risk in CRS management.
Abstract

Related Concept Videos

Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Epistaxis01:30

Epistaxis

Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...