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Visceral leishmaniasis revealed by a squamous cell carcinoma in an HIV-1 infected patient
P Donati1, G Paolino, C Panetta
1Dermatopathology Unit, San Gallicano Dermatological Institute (IRCCS), Via Elio Chianesi, 53, 00144, Rome, Italy.
Abstract:
We present a case of visceral leishmaniasis confirmed after the histological investigation of an ulcerate lesion of the scalp in an HIV-1-infected patient receiving highly active antiretroviral therapy (HAART). Histological examination of the skin lesion revealed a squamous cell carcinoma superinfected by amastigotes of Leishmania infantum from the bloodstream. Because HIV-1-infected individuals can harbour parasitic infections in normal and neoplastic tissue, it is necessary to examine carefully any skin lesions, particularly those with uncommon aspects or a worsening course, to exclude superinfections by unsuspected pathogens.
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