Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cell Size

Cell Size

Cell sizes vary widely among and within organisms. Bacterial cells range between 1-10 micrometers (μm)and are considerably smaller than most eukaryotic cells. The smallest bacteria are 0.1 μm in diameter—about a thousand times smaller than eukaryotic cells, which typically range from 10-100 μm.
Surface Area
Cells can take in nutrients and water via diffusion through the plasma membrane itself or through specific channels in the membrane. The area of the membrane surrounding the cells limits the...

Area Problem

Area Problem

Determining the area of a region with straight edges is straightforward, as geometric formulas for rectangles, triangles, and polygons can be applied directly. However, traditional geometric methods are insufficient when a region has a curved boundary, such as the area under a function.fromThe area problem involves finding a systematic way to measure such regions. One approach to solving this problem is through approximation. Instead of attempting to compute the area exactly at the outset, the...

Area of a Surface of Revolution

Area of a Surface of Revolution

Surfaces of revolution are formed when a two-dimensional curve is rotated around an axis, producing a three-dimensional shape. This concept is used in engineering tasks like determining the surface area of a rocket nozzle, where precise calculations are critical for applying uniform heat-resistant coatings. When a curve is revolved about the x-axis, it sweeps out a continuous surface whose area must be calculated accurately to estimate material requirements.Approximating with Conical BandsTo...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Comparison of microglial cell population expansion in the <i>Tg344-AD</i> rat and <i>APP<sub>SWE</sub>/PS1<sub>ΔE9</sub></i> mouse model of Alzheimer's disease.

Journal of Alzheimer's disease reports·2025

Same author

The porcine corticospinal decussation: A combined neuronal tracing and tractography study.

Brain research bulletin·2018

Same author

Space Balls Revisited: Stereological Estimates of Length With Virtual Isotropic Surface Probes.

Frontiers in neuroanatomy·2018

Same author

Disturbances in the control of capillary flow in an aged APP<sup>swe</sup>/PS1ΔE9 model of Alzheimer's disease.

Neurobiology of aging·2017

Same author

Neuron and neuroblast numbers and cytogenesis in the dentate gyrus of aged APP<sub>swe</sub>/PS1<sub>dE9</sub> transgenic mice: Effect of long-term treatment with paroxetine.

Neurobiology of disease·2017

Same author

Stereological investigation of the CA1 pyramidal cell layer in untreated and lithium-treated 3xTg-AD and wild-type mice.

Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft·2016

Search research articles

Related Experiment Video

Updated: May 14, 2026

Serial Block-Face Scanning Electron Microscopy (SBF-SEM) of Biological Tissue Samples

Serial Block-Face Scanning Electron Microscopy (SBF-SEM) of Biological Tissue Samples

Published on: March 26, 2021

Estimating surface area in biological structures.

Cold Spring Harbor Protocols

|February 5, 2013

Summary

This study details stereological methods for estimating surface area in biological structures. These techniques provide crucial insights into normal and pathological processes, using the human brain

Area of Science:

Stereology and quantitative morphology
Biological surface area estimation
Neuroanatomy and organ system analysis

Background:

Stereological methods are vital for understanding biological structures.
Estimating surface area is key to analyzing normal and pathological processes.
Previous research highlights the importance of surface area in biological contexts.

Purpose of the Study:

To describe the process of estimating surface area in biological structures.
To discuss relationship equations and procedures for surface area estimation.
To provide a practical example of surface area estimation in the human brain.

Main Methods:

Application of stereological principles for surface estimation.
Utilizing established relationship equations for surface area calculations.

More Related Videos

Exploring Adipose Tissue Structure by Methylsalicylate Clearing and 3D Imaging

Exploring Adipose Tissue Structure by Methylsalicylate Clearing and 3D Imaging

Published on: August 19, 2020

Extracting Metrics for Three-dimensional Root Systems: Volume and Surface Analysis from In-soil X-ray Computed Tomography Data

Extracting Metrics for Three-dimensional Root Systems: Volume and Surface Analysis from In-soil X-ray Computed Tomography Data

Published on: April 26, 2016

Related Experiment Videos

Last Updated: May 14, 2026

Serial Block-Face Scanning Electron Microscopy (SBF-SEM) of Biological Tissue Samples

Serial Block-Face Scanning Electron Microscopy (SBF-SEM) of Biological Tissue Samples

Published on: March 26, 2021

Exploring Adipose Tissue Structure by Methylsalicylate Clearing and 3D Imaging

Exploring Adipose Tissue Structure by Methylsalicylate Clearing and 3D Imaging

Published on: August 19, 2020

Extracting Metrics for Three-dimensional Root Systems: Volume and Surface Analysis from In-soil X-ray Computed Tomography Data

Extracting Metrics for Three-dimensional Root Systems: Volume and Surface Analysis from In-soil X-ray Computed Tomography Data

Published on: April 26, 2016

Detailed procedures for estimating surface area in organ system components.

Main Results:

Demonstration of accurate surface area estimation in biological tissues.
Validation of stereological approaches for quantitative analysis.
Successful application to estimate the pial surface area of the human brain.

Conclusions:

Stereological estimation of surface area is a powerful tool in biology.
The described methods offer a standardized approach for surface area analysis.
This technique enhances understanding of both normal physiology and disease states.