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Updated: May 14, 2026

Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis
Published on: May 12, 2019
Large cell neuroendocrine carcinoma (LCNEC) of the urinary bladder: a case report
Cristina Colarossi1, Piero Pino, Dario Giuffrida
1Pathology Unit, Department of Experimental Oncology, Mediterranean Institute of Oncology, Via Penninazzo 7, Viagrande, (CT), Italy.
Abstract:
Neuroendocrine carcinoma of the urinary bladder is a rare entity, accounting less then 1% of urinary bladder malignancies. The vast majority of the neuroendocrine carcinoma of the urinary bladder is represented by small cell neuroendocrine carcinoma while just few cases of large cell neuroendocrine carcinoma (LCNEC) have been reported. In this cases report we describe a rare case of primary bladder LCNEC.
Virtual Slides:
The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2474700528951562.