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Updated: May 14, 2026

High Yield Purification of Plasmodium falciparum Merozoites For Use in Opsonizing Antibody Assays
Published on: July 17, 2014
Presentation of pediatric malaria to a Canadian children's hospital
Sergio T Fanella1, Hailey Lipkin, Maryanne E Crockett
1Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada. umfanell@cc.umanitoba.ca
Abstract:
The aim of this study was to review the aspects of malaria at a Canadian pediatric hospital and to identify gaps in management. Thirty-eight cases were diagnosed in patients with an average age of 8.4 years, the majority of which were due to Plasmodium falciparum. Two required intensive care, but survived. The majority of patients were immigrants/refugees, and accounted for almost all cases over the last 8 years of review.
Insights
This study reviewed pediatric malaria cases in Canada, finding Plasmodium falciparum was the most common cause. Most cases involved immigrant children, highlighting potential gaps in malaria management for this population.
Area of Science:
- Pediatric infectious diseases
- Tropical medicine
- Public health
Background:
- Malaria remains a significant global health concern, posing risks to travelers and immigrant populations.
- Understanding the epidemiology and management of malaria in non-endemic countries is crucial for effective public health strategies.
Purpose of the Study:
- To analyze the characteristics of malaria cases diagnosed at a Canadian pediatric hospital.
- To identify potential gaps in the clinical management of pediatric malaria.
Main Methods:
- Retrospective review of all pediatric malaria cases diagnosed over a specified period.
- Data collection included patient demographics, malaria species, treatment, and outcomes.
Main Results:
- Thirty-eight cases of pediatric malaria were identified, with an average patient age of 8.4 years.
- Plasmodium falciparum was the predominant species identified.
- The majority of cases involved immigrant or refugee children, particularly in recent years.
Conclusions:
- Pediatric malaria in this Canadian hospital setting is primarily seen in immigrant/refugee children, predominantly caused by P. falciparum.
- The findings suggest a need to review and potentially enhance malaria management protocols for pediatric populations, especially those with a history of travel or immigration.
