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Biphenyls, a new class of compound that inhibits platelet-activating factors
T Takeya1, N Takeuchi, T Kasama
1Showa College of Pharmaceutical Sciences, Tokyo, Japan.
Chemical & Pharmaceutical Bulletin
|February 1, 1990
Abstract:
Honokiol (1), a constituent of Magnoliae cortex, and related synthetic biphenyls inhibited the platelet aggregation induced by a few aggregating agents. In particular, compounds 3, 5, and 10 had an inhibitory effect on platelet activating factor (PAF), which provides a new class of PAF inhibitor.