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Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts
Published on: March 26, 2015
Two-year outcome with the AperFix system for ACL reconstruction.
John W Uribe1, Dillon Arango, Jeremy Frank
1UHZ Sports Medicine Institute, Doctors Hospital, Baptist Health South Florida, Coral Gables, USA.
Orthopedics
|February 6, 2013
Summary
The AperFix System demonstrates durable fixation for anterior cruciate ligament reconstruction, showing no graft failures and excellent patient outcomes. Minor hardware adjustments were needed in a few cases, with a low overall complication rate.
Area of Science:
- Orthopedic Surgery
- Biomedical Engineering
Background:
- Anterior cruciate ligament (ACL) reconstruction is a common orthopedic procedure.
- Graft fixation is critical for successful ACL reconstruction outcomes.
- The AperFix System is designed for femoral and tibial graft fixation.
Purpose of the Study:
- To evaluate the fixation durability and clinical outcomes of the AperFix System in arthroscopic ACL reconstruction.
- To assess the rate of fixation failure and complications associated with the AperFix System.
Main Methods:
- Retrospective review of 185 knees (180 patients) undergoing ACL reconstruction with the AperFix System.
- Minimum follow-up of 2 years postoperatively.
- Prospective assessment of a subset of patients for radiographs and functional status.
Main Results:
- No fixation failures (graft pullout or positioning loss) were observed.
- No patients required revision ACL reconstruction.
- Minor hardware prominence required modification in 2 knees; tibial screw removal occurred in 4 knees due to discomfort.
- 82% of patients had a KT-1000 side-to-side difference < 3 mm.
- Lysholm and patient satisfaction scores correlated significantly with Tegner activity scores.
Conclusions:
- The AperFix System provides durable femoral aperture fixation in ACL reconstruction.
- The system is associated with excellent clinical outcomes and a low complication rate.
- The AperFix System is a reliable option for ACL graft fixation.