Related Experiment Video
Updated: May 14, 2026
07:15
An Intact Pericardium Ischemic Rodent Model
Published on: September 2, 2021
Prognostic predictors in pericardiectomy for chronic constrictive pericarditis
Se Hun Kang1, Jong-Min Song1, Minsoo Kim1
1Division of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
The Journal of Thoracic and Cardiovascular Surgery
|February 6, 2013
Summary
High early diastolic mitral inflow velocity and diabetes mellitus predict poor prognosis after pericardiectomy for constrictive pericarditis. Echocardiography can help identify high-risk patients.
Area of Science:
- Cardiology
- Cardiac Surgery
- Diagnostic Imaging
Background:
- Prognosis following pericardiectomy for constrictive pericarditis is not well-defined, particularly in Asian populations.
- Causes of constrictive pericarditis vary geographically, necessitating region-specific prognostic factor identification.
Purpose of the Study:
- To identify preoperative prognostic factors and clinical outcomes in patients undergoing pericardiectomy for chronic constrictive pericarditis.
- To evaluate the utility of Doppler echocardiography in predicting outcomes after pericardiectomy.
Main Methods:
- Retrospective analysis of 85 patients with chronic constrictive pericarditis undergoing pericardiectomy.
- Evaluation of preoperative clinical, imaging, and echocardiographic data.
- Follow-up for all-cause mortality over a median of 38.5 months.
Main Results:
- Fifteen patients (17.6%) died during follow-up.
- Higher aspartate aminotransferase, smaller left ventricular end-systolic dimension index, and higher early diastolic mitral inflow velocity were observed in non-survivors.
- Diabetes mellitus (HR 4.610) and high early diastolic mitral inflow velocity (HR 1.050/cm/s) were independent predictors of mortality.
Conclusions:
- Preoperative high early diastolic mitral inflow velocity and diabetes mellitus are associated with poor prognosis after pericardiectomy.
- Doppler echocardiography, specifically early diastolic mitral inflow velocity, is valuable for predicting mortality risk in these patients.
- These findings aid in risk stratification and patient management before pericardiectomy.
Related Concept Videos
01:17Pericarditis III: Medical Management
The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
01:19Pericarditis II: Clinical Features and Diagnostic Tests
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
01:22Pericarditis I: Introduction
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
01:30Cardiomyopathy II: Dilated Cardiomyopathy
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
01:25Pericarditis IV: Nursing Management
Pericarditis, an inflammation of the pericardium, necessitates diligent nursing management to ensure effective patient care and recovery. The initial step in managing pericarditis is a comprehensive patient medical assessment.The patient reports chest pain aggravated by breathing, coughing, and swallowing, which worsens when lying supine. The pain often improves when sitting up and leaning forward. Additional symptoms may include fever, malaise, and, in severe cases, signs of heart failure.
01:29Cardiomyopathy III: Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...