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Related Concept Videos

Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...
Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Acute Pancreatitis II: Pathophysiology01:21

Acute Pancreatitis II: Pathophysiology

The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
Acute Pancreatitis I: Introduction01:25

Acute Pancreatitis I: Introduction

Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...

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Updated: May 14, 2026

Robotic Lateral Pancreaticojejunostomy for Chronic Pancreatitis
08:10

Robotic Lateral Pancreaticojejunostomy for Chronic Pancreatitis

Published on: December 14, 2019

[Chronic pancreatitis with pseudocysts?].

L Veits1, M Vieth, A Agaimy

  • 1Institut für Pathologie, Klinikum Bayreuth, Preuschwitzerstr. 101, 95445 Bayreuth, Deutschland. Lothar.Veits@klinikum-bayreuth.de

Der Pathologe
|February 6, 2013
PubMed
Summary
This summary is machine-generated.

Gross examination of cystic changes in chronic pancreatitis presents diagnostic challenges, especially when tumor tissue is absent. Pancreatic cysts warrant consideration for neoplastic processes alongside common pancreatitis-associated pseudocysts.

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An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation
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An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation

Published on: October 31, 2025

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Robotic Lateral Pancreaticojejunostomy for Chronic Pancreatitis
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An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation
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Published on: October 31, 2025

Area of Science:

  • Gastroenterology
  • Surgical Pathology

Background:

  • Chronic pancreatitis can manifest with cystic changes that complicate gross examination.
  • Distinguishing between pancreatitis-associated pseudocysts and neoplastic cysts is crucial for patient management.

Observation:

  • Gross examination of pancreatic cystic lesions can be ambiguous.
  • The absence of grossly detectable tumor tissue exacerbates diagnostic difficulties.

Findings:

  • Pancreatic cysts, irrespective of gross tumor evidence, necessitate evaluation for neoplastic etiology.
  • Pancreatitis-associated pseudocysts are common but do not exclude underlying neoplastic processes.

Implications:

  • Highlights the importance of considering neoplastic processes in the differential diagnosis of pancreatic cysts.
  • Emphasizes the need for thorough pathological assessment of cystic pancreatic lesions to avoid misdiagnosis.