Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Assessment of nausea.

A Del Favero1, F Roila, C Basurto

  • 1Istituto di Clinica Medica I, Universita' di Perugia, Italy.

European Journal of Clinical Pharmacology
|January 1, 1990
PubMed
Summary

Three nausea measurement scales showed similar results in 849 patients undergoing chemotherapy. Researchers found no advantage of analogue scales over discrete scales for assessing nausea intensity.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Upfront pembrolizumab as an effective treatment start in patients with PD-L1 ≥ 50% non-oncogene addicted non-small cell lung cancer and asymptomatic brain metastases: an exploratory analysis.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2021
Same author

Cancer-related fatigue: ESMO Clinical Practice Guidelines for diagnosis and treatment.

Annals of oncology : official journal of the European Society for Medical Oncology·2020
Same author

A randomized, double-blind, placebo-controlled, multicenter study of a ginger extract in the management of chemotherapy-induced nausea and vomiting (CINV) in patients receiving high-dose cisplatin.

Annals of oncology : official journal of the European Society for Medical Oncology·2017
Same author

2016 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting and of nausea and vomiting in advanced cancer patients.

Annals of oncology : official journal of the European Society for Medical Oncology·2016
Same author

MASCC/ESMO Antiemetic Guidelines: Introduction to the 2016 guideline update.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2016
Same author

A review of olanzapine as an antiemetic in chemotherapy-induced nausea and vomiting and in palliative care patients.

Critical reviews in oncology/hematology·2015

Area of Science:

  • Oncology
  • Clinical Pharmacology
  • Biostatistics

Background:

  • Nausea is a common side effect of cancer chemotherapy.
  • Accurate measurement of nausea is crucial for patient care and treatment evaluation.
  • Several methods exist for quantifying nausea, but their comparative performance is not well-established.

Purpose of the Study:

  • To compare the performance of three different nausea measurement scales: discrete scale (DS), visual analogue scale (VAS), and continuous chromatic analogue scale (ACCS).
  • To evaluate the agreement and sensitivity of these scales in measuring nausea across different dimensions (maximal intensity, entity, duration, quantity).

Main Methods:

  • Analysis of data from 849 patients across 4 double-blind, randomized clinical trials and 2 observational studies.

Related Experiment Videos

  • Standardized assessment of nausea using DS, VAS, and ACCS at multiple time points post-chemotherapy.
  • Statistical analysis of scale distributions, inter-scale agreement, and sensitivity across nausea dimensions.

    • Main Results:

    • A uniform distribution of nausea measurements was observed only in patients not receiving antiemetic treatment.
    • Substantial equivalence was found between the DS, VAS, and ACCS scales.
    • No significant advantage of analogue scales (VAS) over discrete scales (DS) was demonstrated.
    • Sensitivity in detecting differences increased with more inclusive assessment dimensions (Quantity > Entity > Maximal Intensity).

    Conclusions:

    • The discrete scale (DS) and analogue scales (VAS, ACCS) demonstrate substantial equivalence in measuring chemotherapy-induced nausea.
    • Nausea assessment benefits from considering multiple dimensions, with quantity being the most sensitive measure.
    • These findings support the use of standardized, multi-dimensional nausea assessment in clinical practice and research.