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Updated: May 14, 2026

Three-dimensional Optical-resolution Photoacoustic Microscopy
Published on: May 3, 2011
Dynamic ultrasound modulated optical tomography by self-referenced photorefractive holography
Emilie Benoit a la Guillaume1, Umberto Bortolozzo, Jean-Pierre Huignard
1Institut Langevin, Ondes et Images, ESPCI ParisTech, CNRS UMR 7587, INSERM U979, Université Paris VI-Pierre et Marie Curie, Paris, France.
Abstract:
Photorefractive Bi(12)SiO(20) single crystal is used for acousto-optic imaging in thick scattering media in the green part of the spectrum, in an adaptive speckle correlation configuration. Light fields at the output of the scattering sample exhibit typical speckle grains of 1 μm size within the volume of the nonlinear crystal. This heterogeneous illumination induces a complex refractive index structure without applying a reference beam on the crystal, leading to a self-referenced diffraction correlation scheme. We demonstrate that this simple and robust configuration is able to perform axially resolved ultrasound modulated optical tomography of thick scattering media with an improved optical etendue.

