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Published on: January 22, 2022
Ovum transmigration after salpingectomy for ectopic pregnancy.
Jackie A Ross1, Amelia Z Davison, Yasmin Sana
1Early Pregnancy and Gynaecology Assessment Unit, Suite 8, Golden Jubilee Wing, King's College Hospital, Denmark Hill, London SE5 9RS, UK. jackie.ross1@nhs.net
Approximately one-third of pregnancies following salpingectomy for ectopic pregnancy result from ovulation contralateral to the remaining fallopian tube. This ovum transmigration occurs frequently and is unlikely to cause ectopic pregnancy.
Area of Science:
- Reproductive Endocrinology
- Gynecologic Surgery
- Clinical Obstetrics
Background:
- Corpus luteum contralateral to tubal ectopic pregnancies observed in 32% of cases.
- Contralateral ovum pick-up rate in intrauterine pregnancies was previously unknown.
Purpose of the Study:
- To determine the proportion of pregnancies resulting from ovum transmigration after salpingectomy for ectopic pregnancy.
- To investigate the incidence of contralateral ovum pick-up in women with a history of unilateral salpingectomy.
Main Methods:
- Retrospective cohort study analyzing clinical and ultrasound records from 1999-2010.
- Included 842 pregnancies in 707 women with prior unilateral salpingectomy for ectopic pregnancy and subsequent spontaneous conception.
- Outcome measure: corpus luteum location relative to the remaining fallopian tube.
Main Results:
- The corpus luteum was contralateral to the remaining tube in 31.6% of pregnancies (266/842).
- No significant difference in contralateral corpus luteum presence between intrauterine (32.0%) and ectopic pregnancies (28.8%).
Conclusions:
- Around one-third of spontaneously conceived pregnancies occur via ovum pick-up from the ovary contralateral to the remaining tube after salpingectomy.
- Contralateral ovum pick-up is common and likely not a primary cause of ectopic pregnancy pathogenesis.
- Further research is needed to understand this phenomenon in women with intact fallopian tubes.
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