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Workshop summary: neotropical primates in biomedical research.

Suzette D Tardif, Christian R Abee, Keith G Mansfield

    ILAR Journal
    |February 6, 2013
    PubMed
    Summary
    This summary is machine-generated.

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    Neotropical primates, or New World monkeys, offer unique advantages for biomedical research due to their physiology. This workshop highlighted their use in studying diseases and developing new research tools.

    Area of Science:

    • Biomedical Research
    • Primatology
    • Comparative Medicine

    Background:

    • Neotropical primates (New World monkeys) are valuable biomedical models due to their distinct physiological characteristics compared to Old World monkeys.
    • Their smaller size, faster maturation, and shorter lifespans make them efficient for various research applications.

    Purpose of the Study:

    • To summarize discussions from an NIH-sponsored workshop on the use of Neotropical primates in biomedical research.
    • To identify challenges and propose actions for the continued development and application of these models.

    Main Methods:

    • Overview of commonly used species: squirrel monkeys, marmosets, and owl monkeys.
    • Presentations on Neotropical primate applications in immunology, infectious disease, neuroscience, and physiology.

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  • Discussion of novel research tools including immune reagents, fMRI, genome sequencing, transgenics, and stem cells.

    • Main Results:

    • Neotropical primates are utilized across diverse research fields, including immunology and neuroscience.
    • Advancements in research tools include marmoset genome sequencing and the first germline transgenic monkey.
    • Challenges were identified in maintaining breeding colonies, developing research tools, and improving colony management.

    Conclusions:

    • Continued use and development of Neotropical primates require support for breeding colonies and research tools.
    • Enhanced networking, training, and veterinary care are crucial for effective research.
    • Developing more affordable and efficient models, including for 'orphan' species, is recommended.