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Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
04:40

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

Published on: August 28, 2018

Coronary artery calcification is associated with the development of hypertension

Chagai Grossman1, Joseph Shemesh, Zamir Dovrish

  • 1Internal Medicine D Meir Hospital, Kfar Saba, Israel.

American Journal of Hypertension
|February 6, 2013
PubMed

Insights

Preexisting coronary artery calcification (CAC) predicts the development of hypertension (HTN). Individuals with CAC had a higher incidence of developing HTN over a 6.6-year follow-up period.

Area of Science:

  • Cardiology
  • Preventive Medicine
  • Medical Imaging

Background:

  • Hypertension (HTN) is a known risk factor for coronary artery calcification (CAC).
  • The relationship between preexisting CAC and the subsequent development of HTN requires further investigation.

Purpose of the Study:

  • To investigate whether preexisting coronary artery calcification (CAC) is associated with the development of hypertension (HTN) in initially normotensive individuals.

Main Methods:

  • A cohort of 483 normotensive subjects (mean age 54) with baseline CAC assessment using computed tomography.
  • Annual follow-up for a mean of 6.6 years to identify new-onset hypertension.
  • Data collected included medical history, physical exams, and laboratory evaluations.

Main Results:

  • 104 subjects developed HTN during follow-up.
  • The incidence of new HTN was higher in subjects with CAC (27%) compared to those without (17%).
  • Preexisting CAC independently predicted HTN development (adjusted hazard ratio 1.63, P=0.04).

Conclusions:

  • Preexisting coronary artery calcification is a significant predictor of developing hypertension.
  • Findings suggest CAC may play a role in the early stages of hypertensive disease.
Abstract

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