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Diuretic use in black patients with uncontrolled hypertension
Linda M Gerber1, Samuel J Mann, Margaret V McDonald
1Department of Public Health, Weill Cornell Medical College, New York, NY, USA. LIG2002@med.cornell.edu
Insights
Despite guidelines, many black patients with uncontrolled hypertension are not prescribed diuretics. This study found that diuretic use was associated with better blood pressure control in this population.
Area of Science:
- Cardiology
- Public Health
- Pharmacology
Background:
- Current hypertension guidelines recommend diuretics as a primary treatment, especially for black patients and those with resistant hypertension.
- Failure to adhere to these recommendations may lead to persistently high rates of uncontrolled hypertension.
- This study investigated diuretic prescribing practices among black patients with uncontrolled hypertension receiving home health care.
Purpose of the Study:
- To assess the prescribing patterns of diuretics in a specific population of black patients with uncontrolled hypertension.
- To identify potential disparities in adherence to hypertension management guidelines.
Main Methods:
- The study involved black participants aged 21-80 with hypertension, identified within an urban home health organization.
- In-home interviews were conducted to collect data on prescribed antihypertensive medications for participants with uncontrolled hypertension.
- Prescribing patterns were analyzed for 658 participants.
Main Results:
- Only 46% of participants were prescribed a diuretic, and 5.5% received no antihypertensives.
- Patients not on diuretics were on fewer medications, had higher diastolic blood pressure (89.2 vs 85.5 mmHg), and were more likely to have systolic blood pressure ≥160 mmHg (57.6% vs 49.0%).
- Diuretic use was linked to lower adjusted systolic (5 mmHg) and diastolic (4 mmHg) blood pressures.
Conclusions:
- A majority of black patients with uncontrolled hypertension in this sample were not receiving recommended diuretic therapy.
- These findings highlight a significant gap between guideline recommendations and clinical practice for hypertension management in this demographic.
- Continued attention and intervention are necessary to improve diuretic prescribing for uncontrolled hypertension in black patients.
Background:
Highly publicized recommendations favor the use of diuretics as a first-line or add-on agent in the management of hypertension, particularly among black patients and patients with resistant hypertension. Failure to follow such guidelines might contribute to high rates of uncontrolled hypertension. This study assessed diuretic prescribing patterns in a sample of black patients with uncontrolled hypertension who were identified from a population of home care recipients.
Methods:
The study was conducted in an urban home health organization. Participants were black, aged 21 to 80 years, and had a diagnosis of hypertension. Participants with uncontrolled hypertension were identified, and in-home interviewers collected information on prescribed antihypertensive medications.
Results:
Of 658 participants, 5.5% were not prescribed any antihypertensives, and only 46% were prescribed a diuretic. Participants who were not taking a diuretic were taking fewer antihypertensive medications (1.7 vs. 2.9; P < 0.0001), had a higher mean diastolic blood pressure (89.2 vs. 85.5; P = 0.0005), and were more likely to have a systolic blood pressure ≥160mm Hg (57.6% vs. 49.0%; P = 0.04). The adjusted mean systolic and diastolic blood pressures were 5 and 4mm Hg lower, respectively, in patients who were taking a diuretic.
Conclusions:
In this sample of black patients with uncontrolled hypertension, despite wide publicizing of the recommendations for use of diuretics, a majority are still not receiving a diuretic. This important issue merits continued attention.
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