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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
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Macular lymphocytic arteritis: first clinical presentation with ulcers.
M Llamas-Velasco1, P García-Martín, J Sánchez-Pérez
1Department of Dermatology, Hospital Universitario de La Princesa, Madrid, Spain. mar.llamasvelasco@gmail.com
Journal of Cutaneous Pathology
|February 7, 2013
Summary
Macular lymphocytic arteritis, a rare vascular condition, typically presents as asymptomatic skin macules. This case highlights ulceration as a new clinical feature, suggesting a link to cutaneous polyarteritis nodosa.
Area of Science:
- Dermatology
- Pathology
- Vascular Biology
Background:
- Macular lymphocytic arteritis is a recently identified condition.
- It is histopathologically defined by lymphocytic arteritis and a hyalinized fibrin ring.
- The condition typically presents as asymptomatic hyperpigmented macules on the lower limbs without systemic disease association.
Observation:
- A case of macular lymphocytic arteritis with ulceration is presented.
- The patient exhibited asymptomatic, progressive eruption of hyperpigmented macules, petechiae, and livedoid lesions.
- Non-traumatic ulcers were observed on the ankle, a previously undescribed finding.
Findings:
- Biopsies confirmed lymphocytic arteritis with fibrinoid necrosis and thrombus.
- Clinical presentation mimicked a pigmented purpuric dermatosis.
- Laboratory tests revealed no significant alterations.
Implications:
- Ulceration in this case may result from chronic lymphocytic damage leading to ischemic damage.
- The presence of ulceration suggests macular arteritis could be a variant or early form of cutaneous polyarteritis nodosa.
- This finding expands the clinical spectrum of macular lymphocytic arteritis.
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