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Negative impact of deep venous thrombosis on chronic venous disease

Francisco S Lozano Sánchez1, José Ramón González-Porras, Santiago Díaz Sánchez

  • 1Department of Angiology and Vascular Surgery, IBSAL-Hospital Universitario de Salamanca, Salamanca, Spain. lozano@usal.es

Thrombosis Research
|February 7, 2013
PubMed

Insights

Deep vein thrombosis (DVT) significantly worsens chronic venous disease (CVD) severity and impacts quality of life (QoL). Early DVT prevention and management are crucial for better patient outcomes.

Area of Science:

  • Vascular Medicine
  • Venous Thromboembolism
  • Quality of Life Research

Background:

  • Chronic venous disease (CVD) can stem from various causes.
  • The impact of CVD etiology on disease severity and patient quality of life (QoL) remains unclear.
  • Investigating whether deep vein thrombosis (DVT) as a cause of CVD influences its outcomes is essential.

Purpose of the Study:

  • To determine if CVD secondary to DVT presents different disease severity and QoL compared to non-DVT CVD.
  • To compare clinical outcomes between patients with CVD caused by DVT and those with non-thrombotic CVD.

Main Methods:

  • A comparative study involving 125 patients with CVD due to DVT and 1435 patients with non-DVT CVD.
  • Disease severity assessed using the CEAP classification and Venous Clinical Severity Score (VCSS).
  • Quality of life evaluated with the Short-Form 12 (SF-12) and Chronic Lower Limb Venous Insufficiency Questionnaire (CIVIQ20).

Main Results:

  • Patients with CVD due to DVT exhibited significantly higher disease severity (CEAP C6 grade, VCSS scores).
  • Poorer quality of life was reported in DVT-related CVD patients (CIVIQ20 and SF-12 global scores).
  • Statistical significance was maintained across all measured severity and QoL parameters.

Conclusions:

  • A history of DVT is associated with increased clinical severity and diminished quality of life in CVD patients.
  • These findings underscore the importance of DVT prevention programs.
  • Implementing strategies to prevent DVT and manage its long-term consequences is recommended.
Abstract

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